ADK — Solanum tuberosum

Summary

PGSC0003DMG400027906, designated ADK (StADK, ATPADK1) on potato chromosome 9, encodes a protein with adenylate kinase family domains and AMP, CMP, UMP and dCMP kinase activities (EC 2.7.4.3) and ATP binding. The product is associated with nucleotide, purine, starch and amino acid metabolism, energy homeostasis, oxidative phosphorylation, detection of nutrient, vegetative phase change, primary root development, positive regulation of autophagy, and response to herbicide. It has been linked to traits including reducing sugar content, starch content, submergence tolerance, stem and leaf senescence, seed yield, flowering time, abscisic acid sensitivity, oxidative stress, high temperature stress, root development, and plant morphology. The protein localises to the chloroplast stroma, mitochondria, cytosol, nucleus, Golgi complex and nuclear ubiquitin ligase complex. Studies of related genes in other species connect the family to energy sensing, metabolic regulation, stress tolerance, starch mobilisation, autophagy, circadian clock periodicity, leaf growth and flowering time.