PFK — Solanum tuberosum

Summary

StPFK (PGSC0003DMG400025455) on potato chromosome 8 encodes a phosphofructokinase with 6-phosphofructokinase and diphosphate-fructose-6-phosphate 1-phosphotransferase activities (EC 2.7.1.11), and contains ATP-binding and metal-binding domains. The gene is associated with glycolytic process, fructose 6-phosphate metabolism, and carbohydrate metabolism, as well as sucrose and starch anabolism. It is also linked to cellular response to hypoxia, response to glucose, root epidermal cell differentiation, and NO storage. The encoded protein localises to the cytosol, cytoplasm, and plasmalemma. StPFK is associated with sugar homeostasis. Studies of related genes in other species link the family to hexose content, leaf size, root morphology, and photochemical quenching, as well as strongly reduced root length with reduced PFK activity.