HMG1 — Solanum tuberosum
Summary
PGSC0003DMG400018679 (HMG1, also known as HMG3) on potato chromosome 3 encodes a hydroxymethylglutaryl-CoA reductase (NADPH) (EC 1.1.1.34), the enzyme that catalyses the committed step of the mevalonate pathway. The gene is associated with the regulation of isoprenoid metabolism, the mevalonate pathway, and sterol, terpene, triterpenoid, saponin, chlorophyll and phytoalexin biosynthesis. It has been linked to steroidal glycoalkaloid content, plant height, biomass, flowering time, male fertility, senescence, wound healing, pigmentation, and responses to jasmonic acid and pathogens. The encoded protein localises to plastid, peroxisome, mitochondrial, chloroplast and ER membranes. Associations with photosynthetic rate and protein content have also been noted. Studies of related genes in other species link the family to isoprenoid biosynthesis, phytosterol content and mevalonate pathway regulation.
Annotations
- Chromosome
- 3
- Related genes
- HMG1, HMG2
- GO terms
- Wound Healing, protein synthesis, regulation of isoprenoid metabolism, secondary metabolism, terpene anabolism, Chloroplast Membrane, Systemic Acquired Resistance, Flower Development
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development