GAPC — Solanum tuberosum

Summary

PGSC0003DMG400017433, designated GAPC and also known as GAPDH, encodes a glyceraldehyde-3-phosphate dehydrogenase (NAD+) with phosphorylating activity, a member of the GlycerAld_3-P_DH family. In potato, this gene is associated with cold-induced sweetening. The encoded protein is linked to diverse molecular functions including oxidoreductase activity, NAD(P) binding, fructose-bisphosphate aldolase activity, phospholipase D activity, and salicylic acid binding. It localizes to multiple cellular compartments such as the plasma membrane, mitochondrial envelope, chloroplast envelope, vacuole, and plant cell wall. Associations extend to grain yield, starch and sugar content, nitrogen content, photosynthetic rate, water use efficiency, and responses to salt, drought, freezing, UV-B, and high temperature stress. Studies of related genes in other species connect the family to disease resistance, thermotolerance, chilling tolerance, and root-knot nematode susceptibility.