4CL2 — Solanum tuberosum

Summary

PGSC0003DMG400014223, the potato 4CL2 gene on chromosome 3, encodes a 4-coumarate--CoA ligase 2 protein. This enzyme possesses multiple CoA-ligase activities, including 4-coumarate-CoA ligase, benzoate-CoA ligase, trans-feruloyl-CoA synthase, (E)-caffeate-CoA ligase, and trans-cinnamate-CoA ligase activities, and binds ATP. The gene is associated with phenylpropanoid, cinnamic acid, ferulate, and anthocyanin metabolism, as well as suberin biosynthesis, wound healing, and phytoalexin biosynthesis. It has been linked to anthocyanin content. The encoded protein localizes to the cytosol and cytoplasm. Studies of related genes in other species connect this family to 4-coumarate-CoA ligase (EC 6.2.1.12) and other CoA-ligase activities.