CYP71D4 — Solanum tuberosum

Summary

PGSC0003DMG400010525, symbol CYP71D4, is a cytochrome P450 gene on potato chromosome 4. It encodes a protein belonging to the CYP71D subfamily with tabersonine 16-hydroxylase, germacrene A hydroxylase, and 5-epi-aristolochene-1,3-dihydroxylase activities, along with monooxygenase, oxidoreductase, heme-binding, iron-binding, and NAD+-binding functions. The product is localised to the endoplasmic reticulum membrane. This gene is associated with antibiotic, hydrocarbon, and ergosterol anabolism, the mevalonate pathway, regulation of hormone levels and signal transduction, response to abiotic stimulus, pre-harvest sprouting, malate secretion, pectin and steroid metabolism, and host invasion. It has been linked to agronomic traits including leaflet number, fruit type and size, starch yield and content, plant dry weight, anthocyanin content, drought sensitivity and tolerance, stomatal opening, and salt tolerance. Studies of related genes in other species connect the family to various hydroxylase activities.