G6PD2 — Solanum tuberosum

Summary

PGSC0003DMG400010802 (G6PD2, also known as STG6PDH) on potato chromosome 5 encodes a glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) with G6P_DH and NAD(P)-binding domains. The enzyme is associated with NADPH regeneration, the pentose-phosphate shunt, and oxidative branch of the pentose pathway. It has been linked to glucose metabolism, sucrose and starch breakdown, starch and anthocyanin anabolism, cell wall polysaccharide biosynthesis, glycan biosynthesis, glutathione metabolism, methionine metabolism, hormone metabolism, secondary metabolism, protein synthesis, and response to water. The product localises to the chloroplast stroma, cytosol, mitochondria, Golgi complex, and plant-type vacuole. Associations with starch yield, reducing sugar content, glucose content, sugar content, anthocyanin content, nitrate uptake, leaf composition, seedling growth, leaf development, cell proliferation, and signal transduction have been noted. Studies of related genes in other species link the family to organ size and calcium signaling.