HSP70 — Solanum tuberosum

Summary

PGSC0003DMG400000444 (HSP70) on potato chromosome 11 encodes a member of the heat shock protein 70 family, a chaperone with ATP hydrolase activity that binds ATP and heat shock proteins and is involved in protein folding. The gene is associated with responses to abiotic stress, virus infection, and the immune response, as well as with protein refolding, the ERAD pathway, and the unfolded protein response in the endoplasmic reticulum. It is linked to detoxification, regulation of hormone levels, nucleosome assembly, and metabolism of sterols, fatty acids, sucrose, and lipids. Associations also include chlorophyll fluorescence, nitric oxide storage, and virus-induced post-transcriptional gene silencing. The encoded protein localises to the cytoplasm, nucleus, membrane, tonoplast, chloroplast membrane, and ER lumen. The gene is further connected to proline content and net photosynthetic rate. Studies of related genes in other species link the family to similar chaperone and stress-response functions.