NPR1 — Solanum lycopersicum

Summary

SOLYC07G044980.3, the tomato NPR1 gene (also known as SlNPR3) on chromosome 7, encodes a transcription cis-regulatory region binding protein with protein homodimerization activity and zinc binding capability. It belongs to the NPR family, containing NPR_central, BTB/POZ, and ankyrin repeat domains. In tomato, NPR1 is associated with resistance to Botrytis cinerea, bacterial wilt, and bacterial leaf spot, as well as disease susceptibility. The gene is linked to salicylic acid signaling, disease resistance, aphid resistance, and coronatine sensitivity. It has been connected to numerous traits including root dry weight, drought sensitivity, bacterial blight resistance, net photosynthetic rate, water use efficiency, chlorophyll content, and salt tolerance. NPR1 localizes to the nucleus, cytoplasm, and plasma membrane, and is associated with salicylic acid anabolism, nuclear transport, and signaling pathways. Studies of related genes in other species link the family to pathogen defense, virus resistance, and osmotic stress tolerance.