MAN — Solanum lycopersicum

Summary

SlMAN (SOLYC07G056220.3) encodes a VPS16 family protein containing Vps16_N, Vps16_C, and WD40 repeat domains, and is associated with SNARE-mediated membrane fusion and protein binding. In tomato, SlMAN is linked to vacuolar protein sorting, late endosome-to-vacuole and Golgi-to-vacuole transport, membrane fusion, amyloplast organization, N-glycan processing, glycoprotein breakdown, hormone metabolism including ethylene anabolism, nitric oxide storage, cell wall organization, fruit development and ripening, and negative gravitropism. The protein localizes to the HOPS and CORVET complexes, trans-Golgi network transport vesicles, multivesicular bodies, late endosomes, tonoplast, vacuole, and endoplasmic reticulum. SlMAN has been connected to leaf morphology, embryo development, seedling growth, stomatal opening, seed development, flowering time, root morphology, salt tolerance, plant height, gravitropism, and pollen tube growth. Studies of related genes in other species link the VPS16 family to vacuole biogenesis, cell elongation, cell division orientation, and flowering time.