M2 — Solanum lycopersicum

Summary

SlM2 (SOLYC06G051650.4) on tomato chromosome 6 encodes a cyclophilin-type peptidylprolyl cis-trans isomerase (PPIase) with a cyclophilin-type PPIase domain. The protein is annotated with cis-trans proline isomerase activity, salicylic acid binding, histone binding, and chromatin binding, among other molecular functions. SlM2 is associated with diverse biological processes including protein proline isomerization, RNA positioning, and androgen anabolism. It is linked to numerous agronomically relevant traits such as fruit dry weight, fruit size, sucrose content, photosynthetic rate, respiration rate, and responses to temperature stress, light intensity, and auxin. The gene is also connected to phenotypes including heat stress tolerance, disease resistance, and root hydrotropism. Studies of related genes in other species link the family to water stress tolerance, cold stress response, and embryo patterning.