RHD2 — Solanum lycopersicum

Summary

Solyc03g117980.3 (RHD2/WFI1) encodes a protein containing NADPH oxidase, FAD-binding, ferric reductase, and EF-hand calcium-binding domains, with NAD(P)H oxidase H2O2-forming activity, calcium ion binding, and multiple kinase activities. In tomato, the gene is associated with bacterial defense, reactive oxygen species biosynthesis, immune response signaling, callose deposition, salicylic acid biosynthesis, and root epidermal cell differentiation. It is linked to numerous agronomic traits including grain yield, seed yield, biomass yield, water use efficiency, net photosynthetic rate, transpiration rate, leaf rolling response, bacterial blight disease resistance, aphid response, aluminum sensitivity, phosphorus uptake, root hair length and development, osmotic stress sensitivity, and brassinosteroid and ethylene sensitivity. The gene product localizes to multiple cellular compartments including the endosome, ER, Golgi, plastid, and vacuole. Studies of related genes in other species link the family to salt stress tolerance, reactive oxygen species homeostasis, and pathogen resistance.