Tm-2 — Solanum lycopersicum

Summary

SOLYC04G009240.2, the tomato Tm-2 gene on chromosome 4, encodes a protein with domains including NB-ARC, LRR, and Rx_N, and binds ADP and ATP. The gene is directly associated with resistance to Tomato mosaic virus and other tobamoviruses, and with antiviral defence, programmed cell death, and the hypersensitive response. It is linked to immune signalling, defence against other organisms, and localisation to the cytoplasm and plasma membrane. The gene is also associated with sugar content. Studies of related sequences in other species connect the family to resistance against Fusarium fungi.