HMG1 — Solanum lycopersicum
Summary
SOLYC02G082260.3 (HMG1) encodes a hydroxymethylglutaryl-CoA reductase (HMGR) with NADPH activity, a key enzyme in the mevalonate pathway. The gene is associated with terpenoid, carotenoid, sterol, and isoprenoid metabolism, as well as lycopene and anthocyanin content. It has been linked to fruit growth and development, pigmentation, photosynthetic rate, sugar content, and disease tolerance. Associations also include plant height, biomass, flowering time, male fertility, senescence, and herbivore resistance. The product localises to the ER and peroxisome membranes. Studies of related genes in other species link the family to isoprenoid and phytosterol biosynthesis and mevalonate pathway regulation.
Annotations
- Chromosome
- 2
- Related genes
- HMG1, HMG2
- GO terms
- homeostasis, Learning, Feeding Behavior, oviposition, NO storage, cholesterol anabolism, lipoprotein metabolism, secondary metabolism
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development