F3H — Solanum lycopersicum

Summary

SOLYC02G083860.3, the tomato F3H gene on chromosome 2, encodes a 2-oxoglutarate-dependent dioxygenase with flavanone 3-dioxygenase, flavonol synthase and chalcone isomerase activities. In tomato, F3H is associated with stress tolerance, anthocyanin breakdown, flavonol and flavonoid metabolism, lycopene and carotenoid biosynthesis, ascorbate production, hormone and terpenoid metabolism, fruit abscission, and fermentation. The protein localises to the cytosol, nucleus, tonoplast and endoplasmic reticulum. F3H is linked to fruit colour, size, dry weight, sugar and carotene content, flower and sepal colour, pollen fertility and thermotolerance, seed dormancy, drought tolerance, oxidative stress response, stomatal resistance, root hair formation, powdery mildew resistance, and circadian clock regulation. Studies of related genes in other species connect the family to seed coat pigmentation, UV-B tolerance and flavonol biosynthesis.