HSP70 — Pisum sativum

Summary

PSAT1G197400 (symbol HSP70) on garden pea chromosome 1LG6 encodes a member of the heat shock 70 family, with ATP hydrolase activity, ATP binding, heat shock protein binding, and protein folding chaperone functions. The gene is associated with protein folding and refolding, mitochondrial protein import and biogenesis, ERAD pathway, ER unfolded protein response, S-nitrosylation and S-transnitrosylation, DNA replication, cell development, embryogenesis, seed maturation, response to virus and stress, and protein targeting. Its product localises to the ER chaperone complex and lumen, chloroplast membrane, cytoplasm, nucleus, and axonemal central pair projection. Studies of related genes in other species link the family to RNase H-like domains, though this is not established for pea HSP70.