FRD1 — Phaseolus vulgaris

Summary

PHAVU_010G101500, designated PvFRD1, encodes a protein with iron chelate reductase activity, also associated with NAD(P)H oxidase H2O2-forming and peroxidase activities, and calcium ion binding. The protein contains Fe3_Rdtase_TM_dom, Fe_red_NAD-bd_6, FAD-bd_8, FAD-bd_FR_type, and FNR_nucleotide-bd domains. In French bean, PvFRD1 is linked to siderophore-iron import, multicellular organismal iron ion homeostasis, and response to bacteria, and localizes to the plasmalemma and nucleus. It is associated with photosynthetic rate, iron acquisition, iron deficiency tolerance, chilling tolerance, disease resistance, root growth under iron deficiency, and metal ion homeostasis. Related genes in other species connect the family to iron metabolism and chlorophyll content, while sequence similarity links PvFRD1 to traits including root system iron content, net photosynthetic rate, cadmium concentration, and oxidative stress response.