PMIT1 — Phaseolus vulgaris

Summary

PvPMIT1, encoded by the gene PHAVU_010G160800 on chromosome 10 of French bean (Phaseolus vulgaris), is a member of the NRAMP family of metal ion transporters. The gene product exhibits metal ion transmembrane transporter activity, including iron channel activity and transporters for manganese, cadmium, and aluminium ions. PvPMIT1 is associated with the transport and homeostasis of multiple metals, including iron, manganese, cadmium, lead, and aluminium, as well as responses to manganese starvation and aluminium stress. The protein localises to the endosome membrane and plasmalemma. Phenotypic associations link the gene to manganese and iron uptake, seed iron accumulation and loading, manganese toxicity tolerance and translocation, and root growth. Studies of related genes in other species connect the family to plant growth, cadmium sensitivity and tolerance, lateral root growth, iron toxicity resistance, and traits such as leaf chlorosis, root morphology, and stomatal opening.