ALS — Phaseolus vulgaris

Summary

PHAVU_009G222201, designated PvALS, encodes an acetolactate synthase (ALS) on French bean chromosome 9. The enzyme possesses acetolactate synthase and pyruvate decarboxylase activities, binds thiamine pyrophosphate, FAD, and magnesium, and localises to the chloroplast stroma as part of the acetolactate synthase complex. PvALS is associated with branched-chain amino acid biosynthesis, including valine anabolism, and with response to herbicide. A specific G121A alteration in this gene is linked to herbicide tolerance. Studies of related genes in other species connect the family to imidazolinone and sulfonylurea herbicide sensitivity and resistance, as well as to seed weight, plant height, nitrogen content, amino acid content, salt response, and overall plant growth and development.