CAF — Phaseolus vulgaris

Summary

PHAVU_009G260000, also known as PvCAF, encodes a protein on chromosome 9 of French bean (Phaseolus vulgaris). The product contains RNase III, PAZ, dsRBD, and DEAD/DEAH box helicase domains and exhibits ribonuclease III, helicase, RNA methyltransferase, and miRNA binding activities. PvCAF is associated with pri-miRNA and pre-miRNA processing, siRNA and ta-siRNA processing, gene silencing by miRNA-directed mRNA cleavage, and regulation of adaxial/abaxial pattern formation, seed maturation, meristem development, and cell fate specification. The protein localizes to the nucleus, D-body, and nucleolus. PvCAF has been linked to numerous traits including leaf, floral organ, and inflorescence morphology, plant embryo development, viral disease response, osmotic sensitivity, root development, and vegetative vigor. Studies of related genes in other species connect the family to microRNA biogenesis, small RNA stability, embryo and floral development, and Sclerotinia sclerotiorum resistance.