GAPC — Phaseolus vulgaris

Summary

PHAVU_009G168500, designated PvGAPC, encodes a glyceraldehyde-3-phosphate dehydrogenase (GAPDH) on French bean chromosome 9. The product possesses glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) and (NADP) activities, along with fructose-bisphosphate aldolase, phospholipase D, voltage-gated anion channel, and histone acetyltransferase activities, and binds NAD, NADP, phosphate, salicylic acid, and double-stranded methylated DNA. PvGAPC is associated with glycolytic, gluconeogenic, pentose-phosphate, and aerobic respiration processes, redox and ROS metabolism, nitrogen fixation, auxin transport, DNA damage response, and flocculation. It localizes to the plasma membrane, mitochondrial envelope, chloroplast envelope, vacuole, apoplast, cell wall, and microtubule cytoskeleton. The gene is linked to grain yield, drought and salt tolerance, freezing tolerance, photoperiod sensitivity, stem and leaf senescence, root morphology, stomatal closure, and disease tolerance. Studies of related genes in other species connect the family to biomass, leaf senescence, and heat stress response.