ADH — Phaseolus vulgaris

Summary

PHAVU_009G134700 (PvADH) on chromosome 9 of French bean encodes a protein with S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] and aldo-keto reductase (NAD) activities, containing ADH zinc-binding and NAD(P)-binding domains. The gene is associated with responses to hypoxia, flooding, water, cold, hydrogen peroxide, sucrose, estradiol, and caffeine, as well as cellular respiration, methanal catabolism, and osmotic and salinity responses. It is linked to traits including drought tolerance, herbicide sensitivity, seed weight and size, germination rate, photosynthetic rate, pollen fertility, disease tolerance, and low-temperature stress response. Phenotypic associations include hypoxia, submergence, waterlogging, cold, and salt stress tolerance, fermentation, aldehyde detoxification, and allyl alcohol resistance. Studies of related genes in other species connect the family to low oxygen tolerance, cold and drought resistance, and pathogen resistance.