NRAMP1 — Phaseolus vulgaris

Summary

PHAVU_009G127900, designated PvNRAMP1, encodes a member of the NRAMP family of metal ion transporters. The gene product exhibits metal ion transmembrane transporter activity, including iron channel activity, manganese ion transmembrane transporter activity, and aluminium ion transporter activity. PvNRAMP1 is associated with the transport of aluminium, iron, and manganese ions, as well as cellular homeostasis of iron and manganese. It is linked to the response to aluminium and to nitric oxide storage. The protein localises to the plasmalemma. In French bean, PvNRAMP1 is connected to related genes NRAMP7.1 and CTL16. Studies of related genes in other species link the family to the transport of essential and toxic metal ions, supporting a conserved role in metal homeostasis.