DMT1 — Phaseolus vulgaris

Summary

PHAVU_003G238600, designated DMT1 (PvDMT1) on chromosome 3 of French bean (Phaseolus vulgaris), encodes a member of the NRAMP family of metal ion transporters. The gene product possesses metal ion transmembrane transporter activity, specifically for manganese ions, and is associated with manganese and iron ion membrane transport, cellular metal ion homeostasis, and responses to iron and zinc. It is linked to lead ion transport, regulation of vacuolar transport, positive regulation of ROS metabolic process, and defence responses to bacteria and nematodes. The protein localises to the vacuolar membrane, trans-Golgi network, plasmodesmata, plastid, and Golgi. Associations include copper homeostasis, iron remobilisation and iron localisation in seeds, growth under manganese deficiency, and seed germination. Related genes in other species link the family to iron deficiency responses, manganese and zinc accumulation, cadmium transport, photosystem II function, and pathogen resistance.