F3H — Phaseolus vulgaris

Summary

PHAVU_003G261900, designated PvF3H (also known as TT6 or PvF3'H), encodes a flavanone 3-dioxygenase on chromosome 3 of French bean (Phaseolus vulgaris). The product belongs to the Fe2OG dioxygenase superfamily and exhibits flavone synthase, flavonol synthase, and chalcone isomerase activities, along with vitamin C and metal binding. PvF3H is associated with anthocyanin, flavonoid, and coumarin biosynthesis, responses to UV-B, UV light, fungal molecules, and auxin, and is localized to the cytosol, ER, tonoplast, and nucleus. The gene is linked to flower and seed coat color, stamen morphology, root phototropism, UV-B sensitivity, oxidative stress response, proanthocyanidin accumulation, cold acclimation, lateral root development, photosynthetic activity, circadian clock regulation, and pathogen response. Studies of related genes in other species connect the family to seed pigmentation, anthocyanin content, UV-B tolerance, and flavonol synthesis.