GAPC — Phaseolus vulgaris

Summary

PHAVU_001G259000, designated PvGAPC on chromosome 1 of French bean (Phaseolus vulgaris), encodes a glyceraldehyde-3-phosphate dehydrogenase (GAPDH) family protein with glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, as well as NADP-dependent GAPDH, fructose-bisphosphate aldolase, phospholipase D, voltage-gated anion channel, and histone acetyltransferase activities. The gene is associated with glycolytic and gluconeogenic processes, the pentose-phosphate shunt, aerobic respiration, redox and ROS metabolic responses, anoxia response, nitrogen fixation, auxin polar transport, and cell cycle modulation. It localizes to the plasma membrane, mitochondrial and chloroplast envelopes, vacuole, apoplast, cell wall, and microtubule cytoskeleton. PvGAPC is linked to grain yield, drought and salt tolerance, freezing tolerance, stem and leaf senescence, photoperiod sensitivity, root morphology, disease tolerance, and seed oil accumulation. Studies of related genes in other species connect the family to biomass, leaf senescence, and heat, chilling, and anaerobic stress responses.