NAS1 — Phaseolus vulgaris

Summary

PvNAS1 (PHAVU_001G225000) on chromosome 1 of French bean (Phaseolus vulgaris) encodes a nicotianamine synthase, an enzyme with nicotianamine synthase activity that belongs to the nicotianamine synthase domain family and the SAM-dependent methyltransferase superfamily. This gene is associated with nicotianamine anabolism, response to zinc, nitrogen fixation, phloem transport, pollen tube growth, and pollen development, and its product localizes to the nucleus. It has been linked to cadmium tolerance, iron translocation, chlorosis, iron deficiency tolerance, and rRNA gene expression. Studies of related genes in other species connect the family to iron homeostasis, iron transport, zinc content, iron accumulation, cadmium detoxification, and iron deficiency response, as well as chlorotic leaves, altered metal content, and increased iron uptake.