PMIT1 — Oryza sativa Japonica

Summary

OsPMIT1 (OS12G0581600) encodes a member of the NRAMP family of metal ion transporters, with molecular functions including manganese, cadmium, and iron channel transmembrane transporter activity. The gene is associated with multiple aspects of metal homeostasis and stress responses in rice. It has been linked to cadmium accumulation and tolerance, manganese accumulation and transport, iron uptake, and broad-spectrum disease resistance. Associations with grain cadmium content, grain quality, and yield have been observed, as well as with root development, xylem loading, and vascular bundle function. The encoded protein localizes to the tonoplast, vacuolar membrane, trans-Golgi network, and endosome membranes. Additional associations include biological yield, leaf relative water content, chlorophyll content, plant height, and jasmonic acid content. Studies of related genes in other species link the family to iron mobilization, cadmium sensitivity, and pathogen resistance.