NHX8 — Oryza sativa Japonica

Summary

Os12g0641100 (NHX8, also known as SOS1) encodes a cation/H⁺ exchanger of the CPA1 family with lithium:proton antiporter, sodium:hydrogen exchanger and potassium:proton antiporter activities. The gene is associated with alkaline stress, salt stress resistance, sodium ion efflux and homeostasis, lithium transport and homeostasis, potassium acquisition, and cell pH regulation. It has been linked to yield traits, plant vigor, water use efficiency, photosynthetic rate, chlorophyll content, plant height, germination rate, root development, drought tolerance, high temperature stress response, and disease tolerance. The protein localizes to the vacuolar membrane, tonoplast, plasmalemma, and chloroplast envelope, and is associated with abscisic acid, cytokinin, and nitric oxide anabolism, photoprotection, photorespiration, and lateral root morphogenesis. Studies of related genes in other species link the family to sodium exclusion, ion homeostasis, and salt tolerance.