PI-TA — Oryza sativa Japonica

Summary

OS12G0281300 (symbol PI-TA) in rice (Oryza sativa Japonica) on chromosome 12 encodes a protein containing a thioredoxin domain, an NB-ARC domain, and leucine-rich repeats, characteristic of plant disease resistance proteins. It is annotated with ADP, ATP, and metal binding molecular functions. The gene is associated with defense responses, including innate immune response-activating signaling, antiviral response, and hypersensitive response-programmed cell death, as well as regulation of pattern recognition receptor signaling and secretion. It localizes to the cytosol, cytoplasm, and plasmalemma. PI-TA has been linked to agronomically important traits such as grain weight, grain yield, and amylose content, and to phenotypes including blast resistance, particularly against Magnaporthe oryzae, and disease resistance. Studies of related genes in other species connect the family to additional disease resistance functions.