PMIT1 — Oryza sativa Japonica

Summary

OS07G0257200 (PMIT1, also known as NRAMP5) encodes a member of the NRAMP family of metal ion transporters, with molecular functions including manganese, cadmium, iron, and aluminium ion transmembrane transporter activity. In rice, this gene is associated with the accumulation and tolerance of cadmium and cobalt, manganese uptake and accumulation, grain cadmium content, grain quality, yield, root and shoot development, and lateral root formation. It has also been linked to immunity, broad-spectrum disease resistance, and reactive oxygen species metabolism. The encoded protein localises to the plasma membrane, vacuole, endosome, Golgi, and plasmodesmata. Associations extend to shoot and root dry weight, plant height, chlorophyll content, leaf relative water content, and heterosis. Studies of related genes in other species link the family to iron mobilisation, manganese homeostasis, and pathogen resistance.