PNH — Oryza sativa Indica Group

Summary

BGIOSGA026455 (symbol PNH, preferred name OiPNH) on Indica rice chromosome 7 encodes an Argonaute 7 protein with RNA endonuclease activity and RNA binding, containing Piwi, PAZ, and RNaseH-like domains. It is associated with posttranscriptional gene silencing by RNA, RNA-dependent gene silencing, and regulation of gene expression. The gene is linked to upregulation of meiotic DNA double-strand break formation, male and female meiotic nuclear division, microgametogenesis, megagametogenesis, gametophyte development, and pollen development. It is also associated with maintenance of shoot apical meristem identity, stem cell population maintenance, leaf development, response to jasmonic acid, detoxification, and homeostasis. Localisation evidence places the product in the nucleus, nucleolus, NOR, and cytoplasm. Studies of related genes in other species further support the family's role in RNA silencing pathways.