PMIT1 — Oryza sativa Indica Group

Summary

BGIOSGA024510 (PMIT1, also known as OsNRAMP5) on chromosome 7 of Indica rice encodes a member of the NRAMP family of metal ion transporters, with molecular functions including manganese, iron, cadmium, and aluminium ion transmembrane transporter activity. The gene is associated with manganese, cadmium, and cobalt accumulation and tolerance, as well as iron uptake, disease resistance, and immunity in rice. It has been linked to grain cadmium content, grain quality, yield, root and shoot development, lateral root formation, xylem loading, and reactive oxygen species regulation. The encoded protein localizes to the plasma membrane, vacuole, endosome, Golgi, and plasmodesmata. Related genes in other species are associated with iron mobilization, cadmium sensitivity, and pathogen resistance.