ADH — Oryza sativa Indica Group

Summary

BGIOSGA023892 (symbol ADH, also known as OiADH, OiGSNOR, and HOT5) on chromosome 7 of Indica rice encodes a protein with S-nitrosoglutathione reductase (NADH) activity, S-(hydroxymethyl)glutathione dehydrogenase activity, and aldo-keto reductase activity, belonging to the alcohol dehydrogenase family. The gene is associated with responses to hypoxia, flooding, submergence, and hydrogen peroxide, as well as cellular respiration, the MAPK cascade, heat acclimation, seed development, programmed cell death, and osmotic and salinity responses. It has been linked to traits including respiration rate, photosynthetic rate, plant height, drought tolerance, herbicide sensitivity, leaf senescence, disease tolerance, and salt tolerance. The encoded protein localizes to the plastid, mitochondria, cytosol, plasmalemma, and nucleus. Studies of related genes in other species link the family to hypoxia, dehydration, and cold stress responses, as well as formaldehyde detoxification and nitric oxide signaling.