ERD2 — Oryza sativa Indica Group

Summary

BGIOSGA013836 (symbol ERD2, also known as OiERD2) on indica rice chromosome 3 encodes a member of the Hsp70 family of ATP-dependent protein folding chaperones, containing an ATPase nucleotide-binding domain and the characteristic heat shock 70 conserved signature. The gene product is associated with diverse molecular functions including calcium-dependent phospholipid binding, DXP-synthase activity, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase activity, and Hsp90 binding. It is linked to biological processes such as cell glucose homeostasis, upregulation of cellular defense response, response to humidity, cytosol-to-ER transport, RuBisCO assembly, and protein localization to chloroplast. Associations with agronomically relevant traits include grain yield per plant, spikelet fertility, grain filling period, biomass yield, photosynthetic ability, carotenoid content, herbicide sensitivity, and responses to temperature and salt stress. The gene is also connected to seedling phenotypes and localizes to the ER chaperone complex, mitochondrial outer membrane, and thylakoid lumen.