H6H — Medicago truncatula

Summary

MTR_7G016080 (symbol H6H) in barrel medic (Medicago truncatula) chromosome 7 encodes a 2-oxoglutarate-dependent dioxygenase with multiple annotated activities including mugineic-acid 3-dioxygenase, 2'-deoxymugineic-acid 2'-dioxygenase, hyoscyamine (6S)-dioxygenase, desacetoxyvindoline 4-hydroxylase, flavonol synthase, and flavanone 3-dioxygenase. The gene is associated with responses to iron(III), chalcone anabolism, jasmonic acid anabolism, coumarin anabolism, ethylene anabolism, flavonoid anabolism, and alkaloid metabolism, as well as cell wall modification, phenylpropanoid metabolism, defense response to oomycetes, and response to molecules of fungal origin. Its product localizes to the cytoplasm and nucleus. Plant height is also linked to this gene. Studies of related genes in other species connect the family to further dioxygenase activities (EC 1.14.11.24, 1.14.11.25, 1.14.20.13, 1.14.11.11, 1.14.11.20, 1.14.20.6, 1.14.11.9).