H6H — Medicago truncatula

Summary

MTR_7G016090 (H6H) in barrel medic (Medicago truncatula) on chromosome 7 encodes a 2-oxoglutarate-dependent dioxygenase with mugineic-acid 3-dioxygenase, 2'-deoxymugineic-acid 2'-dioxygenase, hyoscyamine (6S)-dioxygenase, and flavanone 3-dioxygenase activities. The gene is associated with responses to iron(III), fungal and oomycete pathogens, and molecules of fungal origin, as well as the biosynthesis of chalcones, jasmonic acid, coumarins, ethylene, flavonoids, and phenylpropanoids. It is also linked to cell wall modification and phenylpropanoid metabolism. The encoded protein localises to the cytoplasm and nucleus. Additionally, H6H is associated with plant height. Studies of related genes in other species link the family to further dioxygenase activities (EC 1.14.11.25, 1.14.11.24, 1.14.20.13, among others).