ERD5 — Medicago truncatula

Summary

MTR_6G016650 (MtERD5, also known as MtPRO1, MtPDH1, MtPDH2, MtAT-POX, MtATPOX, MtPRODH, MtATPDH, PDH1, ATPDH, PDH2, PRODH) on barrel medic chromosome 6 encodes a proline oxidase with a proline dehydrogenase domain and FAD-linked oxidoreductase-like domain, localised to mitochondria. The gene is associated with proline breakdown, phytochelatin anabolism, the shikimate pathway, nitrogen fixation, cytokinin signaling, cellular response to hypoxia, response to oxidative stress, osmotic response, leaf development, nodulation, cell differentiation, defence response to bacteria, and response to thirst. It has been linked to seed hardness, leaf water potential, biomass yield, photosynthetic rate, seed dormancy, proline accumulation, growth under water deficit, hypersensitive response, root elongation at low water potential, NADP/NADPH ratio, dehydration response, and drought tolerance. Studies of related genes in other species link the family to oxidative stress tolerance, salt tolerance, and response to dehydration.