AKR — Medicago truncatula

Summary

MTR_6G072710 (symbol AKR) in barrel medic (Medicago truncatula) chromosome 6 encodes a protein with an aldo/keto reductase active site and NADP-dependent oxidoreductase domain, exhibiting D-galacturonate reductase, 3''-deamino-3''-oxonicotianamine reductase, aldose reductase (NADPH) and general oxidoreductase activities. The gene is associated with ascorbate biosynthesis, siderophore anabolism, secondary metabolite biosynthesis, and alkaloid anabolism, as well as ecgonine methyl ester and ecgonone methyl ester metabolism. It is linked to responses to iron ion starvation, salt stress, and leaf senescence, and to hypersensitivity. The encoded protein localises to the cytosol. Studies of related genes in other species connect the family to additional NADP-dependent oxidoreductase functions.