LYK3 — Medicago truncatula

Summary

MTR_5G086330, symbol LYK3, encodes a CERK1/LYK3-like transmembrane receptor protein kinase with serine/threonine kinase activity and chitin binding. This barrel medic gene on chromosome 5 is associated with nodulation, nitrogen fixation, and response to symbiotic bacteria, as well as detection of fungal molecules, response to chitin, and innate immune response-activating signaling. It has been linked to regulation of leaf senescence, cell death, endocytosis, vesicle localization, chloroplast organization, post-embryonic development, cell differentiation, and regulation of reactive oxygen species metabolism. The product localizes to the membrane, plasmalemma, and vacuolar lumen. Studies of related genes in other species link the family to additional signaling roles in development and symbiosis.