SS2 — Medicago truncatula

Summary

MTR_4G071520 (symbol SS2, also known as MtERG9) encodes a squalene synthase, an enzyme with squalene synthase activity that also binds metals. The gene is associated with sterol, triterpenoid, isoprenoid, and saponin anabolism, as well as farnesyl diphosphate metabolism and secondary metabolism. Its product localises to the endoplasmic reticulum membrane, the ER, mitochondria, and the plasma membrane. The gene has been linked to responses to vanadate, nitric oxide, hydrogen peroxide, salicylate, fungal molecules, ethylene, and jasmonic acid. Studies of related genes in other species link the squalene synthase family to triterpene, brassinosteroid, and sterol biosynthesis, and to traits such as brassinosteroid content and root length.