SKP1 — Medicago truncatula

Summary

MTR_1G099870, the SKP1 gene on chromosome 1 of barrel medic (Medicago truncatula), encodes a SKP1-like protein containing the SKP1 dimerisation and BTB/POZ superfamily domains. The product binds cullin family proteins and is associated with protein ubiquitination, specifically SCF-dependent proteasomal ubiquitin-dependent protein breakdown. It is linked to cell cycle, cell division, cell motility, secretion, and homeostasis, as well as jasmonic acid (JA) signalling. The gene is connected to leaf development, flower development, and organ growth, with a specific association with leaf size. The protein localises to both the cytoplasm and the nucleus. Related genes in other species (OSK1, OSK5, OSK20) are linked to similar ubiquitination and developmental processes, though these associations are not yet established in barrel medic itself.