ELO3 — Medicago truncatula

Summary

MTR_1G107255 (ELO3, also known as MtEAST1, HAG3, MtHAG3, MtELP3, ELP3, MtHAC8, HAC8, EAST1) on chromosome 1 of barrel medic encodes a protein with a radical SAM domain and a GNAT acetyltransferase domain, characteristic of the Elongator complex protein 3 (ELP3) family. The gene product possesses tRNA uridine(34) acetyltransferase activity, histone acetylase activity, tRNA binding, and 4Fe-4S cluster binding. It is associated with the Elongator holoenzyme complex and localizes to the nucleus, euchromatin, and cytosol. The gene is associated with mcm5 modification, regulation of leaf formation, specification of plant organ axis polarity, organ growth, exocytosis, nitrogen fixation, nodulation, seed germination, cell cycle, cell death, DNA replication and repair, response to virus, and regulation of auxin-mediated signaling. It is also linked to UV-B tolerance and UV-B-induced DNA damage repair, leaf adaxial-abaxial polarity, microtubule association, and aliphatic glucosinolate biosynthesis.