GR — Medicago truncatula

Summary

MTR_1G070505, designated GR (MtGR, GR2), encodes a protein with glutathione reductase, thioredoxin reductase (NADPH), leghemoglobin reductase, and dihydrolipoyl dehydrogenase activities, and binds FAD, NADP, copper, and ATP. In barrel medic, GR is associated with nitrogen fixation, nodulation, cell redox homeostasis, phytochelatin anabolism, glutathione metabolism, flavonoid metabolism, 2-oxoglutarate metabolism, glycine decarboxylation, mitochondrial protein import, and response to cadmium and oxidative stress. It localizes to mitochondrial membranes, the glycine cleavage system, and the KGDHC complex. GR is linked to shoot dry weight, photosynthetic rate, chlorophyll content, salt tolerance, root morphology, leaf senescence, embryo development, stomatal aperture, drought stress response, and photosystem II function. Related genes in other species connect the family to cellular redox homeostasis, heat and cold tolerance, sulfur assimilation, and seed viability.