LOX — Lactuca sativa

Summary

LsLOX, encoded by the garden lettuce gene LSAT_V11C600317400 on chromosome 6, is a lipoxygenase family protein containing iron-binding and PLAT/LH2 domains. It is annotated with linoleate 13S-lipoxygenase and oxidoreductase activities, and is associated with jasmonic acid and oxylipin biosynthesis, green leaf volatile production, and responses to herbivores, insects, ozone, and high light intensity. The gene is linked to wound response, jasmonate accumulation, and defense against herbivory, as well as to traits including nitrate content, photoperiod-sensitive flowering time, seed yield, photosynthetic rate, root thickness, and low temperature stress response. It localises to chloroplast thylakoid membranes, the chloroplast envelope, stromules, and stress granules. Related genes in other species are linked to resistance to fungal pathogens, herbivory, and potyviruses, and to leaf senescence and abiotic stress tolerance.