HGGT — Lactuca sativa
Summary
LsHGGT, encoded by the gene LSAT_V11C500259430 on chromosome 5 of garden lettuce (Lactuca sativa), is a UbiA prenyltransferase family protein with homogentisate geranylgeranyltransferase (HGGT) and homogentisate phytyltransferase (HPT) activity. It is associated with vitamin E and tocomonoenol biosynthesis, fat-soluble vitamin anabolism, and phloem sucrose loading. The protein localises to the chloroplast thylakoid membrane and is linked to cellular responses to UV-B, thermal stimulus, and regulation of defense response. Phenotypic associations include tocopherol biosynthesis, seedling growth, low-temperature adaptation, photo-oxidative stress response, chlorophyll content, bacterial resistance, seed desiccation tolerance, and oxidative stress tolerance. Studies of related genes in other species link the family to photooxidative stress tolerance, seed tocopherol content, salicylic acid accumulation, and transfer cell wall development.
Annotations
- Chromosome
- 5
- Related genes
- HGGT, HPT1
- GO terms
- vitamin E anabolism, Chloroplast Membrane, Cellular Response To UV-B, Regulation Of Defense Response, Chloroplast Thylakoid Membrane, GO:0009507, Prenyltransferase Activity, Cell Wall Organization
- Publications
- 22131159, 23713813, 23651908, 16290217, 29194404, 18452591, PMID:20837525, PMID:16408209
- Traits
- tocopherol biosynthesis, Tocopherol-deficient with anthocyanin accumulation, reduced growth at low temperatures, Tocopherol-deficient with fatty acid desaturation defects and anthocyanin accumulation, Tocopherol-deficient, lacking all tocopherols and pathway intermediates, Fatty acid desaturation deficiency, lacks tocopherols, suppressed cold stress phenotypes, No Lipid Peroxidation Under High Light at Low Temperature, Altered fatty acid composition, abnormal cell wall development at low temperature, Slightly inhibited growth with normal morphology