CYP71D7 — Lactuca sativa

Summary

LsCYP71D7 (CYP71D7, CYP71BL2) on chromosome 1 of garden lettuce (Lactuca sativa) encodes a cytochrome P450 family protein with germacrene A acid 8beta-hydroxylase and costunolide synthase activities, as well as broader oxidoreductase and monooxygenase functions. It is associated with sesquiterpenoid and lactone metabolism and biosynthesis, and with response to jasmonic acid. The protein localises to membranes. Studies of related genes in other species link the CYP71D7 family to additional P450 activities, including EC 1.14.14.170, 1.14.14.168, 1.14.14.150, and 1.14.14.151. The gene is also related to CYP71D6, another P450-encoding gene.

Annotations

Chromosome
1
Related genes
CYP71D7, CYP71D6
GO terms
lactone anabolism, lactone metabolism, sesquiterpenoid metabolism, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Sesquiterpene Biosynthetic Process, terpenoid anabolism, Response To Jasmonic Acid, Membrane
Publications
PMID:29758164, PMID:21858047, PMID:21515683, PMID:30468448, PMID:23757397, PMID:34348650, PMID:25786135, PMID:29086444