PAP5 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.6HG0622180, designated HvPAP5 (also known as HvSAG12), encodes a papain-like cysteine peptidase belonging to the peptidase C1A family, with thiol endopeptidase activity and cysteine-type peptidase activity. In barley, this gene is associated with leaf senescence, programmed cell death, and cell death, as well as responses to the hormones abscisic acid, ethylene, and gibberellin. It is linked to proteolysis, protein breakdown, the mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, developmental processes, and regeneration. The encoded protein localises to the senescence-associated vacuole, protein storage vacuole, lysosome, aleurone body, cytoplasmic vesicle, and ER lumen. Studies of related genes in other species connect this family to similar senescence and proteolytic processes.