THI1 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.5HG0492390 (HvTHI1, also known as HvSAG12) on barley chromosome 5H encodes a cysteine-type peptidase belonging to the papain-like cysteine peptidase family (Peptidase_C1A_papain-like). The gene is associated with leaf senescence, programmed cell death, and proteolysis, and its product localises to senescence-associated vacuoles, protein storage vacuoles, and the ER lumen. HvTHI1 is associated with responses to abscisic acid, ethylene, and gibberellin, as well as with the MVA and MEP pathways. It is associated with salinity, osmotic, and salt stress responses, stomatal closure, resistance to biotic stress, hypoxia response, and organellar DNA damage protection. Studies of related genes in other species link the family to thiamine biosynthesis, grain weight, grain yield, heat tolerance, and drought tolerance.