AXR6 (HORVU.MOREX.R3.3HG0314170) — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.3HG0314170 (HvAXR6) on barley chromosome 3H encodes a cullin family protein with ubiquitin ligase complex scaffold activity, NEDD8 transferase activity, auxin receptor activity, and protein binding, bridging activity. In barley, the gene is associated with grain morphology. It is linked to processes including regulation of ethylene biosynthetic process, protein neddylation, response to organophosphorus, DNA damage response signal transduction, regulation of post-embryonic root development, regulation of gibberellic acid mediated signalling, and regulation of carbohydrate metabolism. The encoded protein localizes to CRL complex, CSN, and nucleotide-excision repair complex. Associations with traits such as Cercospora leaf spot response, bacterial blight disease resistance, photoperiod sensitivity trait, iron content trait, sulfur content, and fruit ripening trait have been noted. Studies of related genes in other species link the family to drought stress, lesion mimic phenotypes, and disease resistance, as well as UV-B tolerance, fertility, and seed oil content.